Good afternoon, dear colleagues,
This week, while speaking with one of my colleagues, he mentioned the following article to me: https://news.doctors.net.uk/opinion/2cqJLQMajnFXyYXAMCTfg?pk_campaign=education%20email.
To summarise, this research found the following:
During the pandemic, a research team in the United Kingdom conducted a controlled ‘challenge trial’ to understand why some people do not contract COVID while others get infected repeatedly. In this study, healthy and unvaccinated volunteers were deliberately exposed to a low dose of the SARS-CoV-2 virus. The researchers monitored the volunteers in a controlled environment and collected samples before and after exposure.
The study found that not all volunteers became infected in the same way. Three groups were identified: one with sustained infection and mild symptoms, another with transient infection and limited symptoms, and a third that neither became infected nor showed symptoms, confirming abortive infections for the first time.
The study also discovered specific immune responses, including a rapid interferon response in the blood before it appeared in the nose, and the presence of a protective gene, HLA-DQA2, in those who did not develop a sustained infection. These findings have important implications for the development of future treatments and vaccines, helping to improve preparedness for future pandemics.
Best regards,
Fernando
NOTE: Thanks, Peter, for the article :)
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