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Depression

Writer's picture: EditorEditor

Updated: Sep 20, 2024

CLINICAL DIAGNOSTIC MANUAL



Depression is a mood disorder characterised by persistent sadness and a loss of interest in activities that were once pleasurable. It is a multifactorial condition that can affect an individual’s daily functioning and quality of life.


The causes of depression can be biological, psychological, and social, and its clinical presentation can range from mild to severe symptoms. Early detection and treatment are essential to improve patient outcomes and quality of life.

Pathology

Symptoms and Clinical Signs

Suspected Diagnosis

Confirmed Diagnosis

Major depression

Depressed mood, anhedonia, appetite and sleep disturbances, fatigue, feelings of worthlessness

Severe symptoms lasting at least two weeks

Clinical evaluation, DSM-5 criteria

Mild to moderate depression

Less severe but persistent depressive symptoms

Depressed mood, difficulty functioning in daily life

Clinical evaluation, depression questionnaires

Reactive depression

Depression following a stressful or traumatic event

History of a clear triggering event

Clinical evaluation, patient history

Medication-induced depression

Depressive symptoms beginning after starting a new medication

Onset of symptoms following the administration of certain medications

Review of medication history, discontinuation of the suspected drug

Seasonal affective disorder

Depression occurring in a specific season, typically in winter

Seasonal patterns of depressive symptoms

Clinical evaluation, DSM-5 criteria


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