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Rash

Writer's picture: Dr Fernando HidalgoDr Fernando Hidalgo

Rashes are a common presentation in the emergency department (ED) and can range from benign to life-threatening conditions. As a junior doctor in emergency medicine, it is important to differentiate between these causes to provide appropriate management and ensure patient safety.

Understanding Rashes

A rash is an area of irritated or swollen skin that may be itchy, red, painful, or blistered. Rashes can be localized or widespread and may present with various characteristics such as macules, papules, vesicles, or pustules.

Common Causes of Rashes

Infectious Causes

  • Viral Exanthems: Such as measles, rubella, and varicella (chickenpox), often associated with systemic symptoms like fever.

  • Bacterial Infections: Impetigo, cellulitis, or scarlet fever.

  • Fungal Infections: Tinea infections (ringworm) affecting different body parts.

  • Parasitic Infections: Scabies or lice infestations.

Allergic Reactions

  • Contact Dermatitis: Caused by exposure to allergens like poison ivy or nickel.

  • Drug Reactions: Such as urticaria (hives) or more severe reactions like Stevens-Johnson syndrome.

Autoimmune and Inflammatory Conditions

  • Psoriasis: Characterized by well-demarcated plaques with silvery scales.

  • Eczema (Atopic Dermatitis): Chronic inflammatory condition causing itchy and red patches.

  • Lupus Erythematosus: Can cause a butterfly-shaped rash on the face.

Other Causes

  • Heat Rash (Miliaria): Caused by blocked sweat ducts in hot and humid conditions.

  • Vasculitis: Inflammation of blood vessels leading to palpable purpura.

Initial Assessment and Management

History Taking

A thorough history is crucial to guide further evaluation:

  • Onset, duration, and progression of the rash

  • Associated symptoms such as fever, itching, pain, or systemic symptoms

  • Recent exposures to allergens, new medications, or infections

  • Travel history or contact with sick individuals

  • Personal or family history of skin conditions

Physical Examination

The physical examination should focus on identifying characteristics of the rash that may indicate specific causes:

  • Distribution and pattern of the rash

  • Type of lesions (e.g., macules, papules, vesicles)

  • Presence of systemic signs such as fever or lymphadenopathy

Diagnostic Workup

Depending on clinical suspicion from history and examination, the following tests may be considered:

  • Skin Swabs or Cultures: For suspected bacterial infections.

  • Blood Tests: Including complete blood count (CBC) and inflammatory markers if systemic involvement is suspected.

  • Skin Biopsy: In cases where the diagnosis is unclear or serious conditions are suspected.

Management Strategies

Management of rashes in the ED focuses on addressing both symptom relief and underlying causes:

  1. Symptomatic Treatment:

    • Antihistamines for itching relief.

    • Topical corticosteroids for inflammatory skin conditions.

  2. Specific Interventions:

    • Antibiotics for bacterial infections.

    • Discontinuation of offending drugs in drug-induced rashes.

  3. Monitoring and Follow-up:

    • Referral to dermatology for chronic or unclear cases requiring further evaluation.

    • Education on avoiding known triggers for allergic reactions.

Challenges and Considerations

Rashes can be challenging due to their broad differential diagnosis. It is crucial to identify red flags that suggest serious underlying conditions requiring urgent intervention. These include widespread blistering, mucosal involvement, signs of systemic illness, or rapidly spreading rashes.

By taking a systematic approach to the assessment and management of rashes, you can effectively address this common complaint in the emergency setting while ensuring appropriate follow-up care.

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